1,6-Dihydro-3 (2H)-pyridinones as synthetic intermediates. Formal synthesis of (±)-tabersonine and (±)-catharanthine |
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| Authors: | Takeshi Imanishi Hiroaki Shin Noriyuki Yagi Miyoji Hanaoka |
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| Affiliation: | Faculty of Pharmaceutical Sciences, Kanazawa University Takara-machi, Kanazawa, 920, Japan |
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| Abstract: | Formal synthesis of (±)-tabersonine (3) and (±)-catharanthine (4) has been achieved starting from ethyl 1,6-dihydro-3 (2H)-pyridinone-1-carboxylate (1a) as a common synthon. |
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