Schiff bases of pyridoxal and polyallylamine. The formation rate determining step

The apparent rate constants of formation (k₁) and hydrolysis (k₂) of the Schiff bases formed between pyridoxal and polyallylamine has been fitted to a kinetic scheme that involve the different protonated species in the reaction medium and the individual rate constants of formation (k₁ⁱ) and hydrolysis (k₂ⁱ). The (k₁ⁱ) values precludes an acid catalyzed intramolecular process. The effects of hydrophobic medium due to the presence of the macromolecule on the reaction is also discussed. © 1998 John Wiley & Sons, Inc. Int J Chem Kinet: 30: 1–6, 1998.