首页 | 本学科首页   官方微博 | 高级检索  
     

a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应:官能化含5-羟基吡唑基的三芳基甲烷类化合物的合成
引用本文:丁旭光,于海丰,赵辉,杨勇. a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应:官能化含5-羟基吡唑基的三芳基甲烷类化合物的合成[J]. 化学通报, 2017, 80(12): 1152-1155
作者姓名:丁旭光  于海丰  赵辉  杨勇
作者单位:鞍山师范学院化学与生命科学学院,鞍山师范学院化学与生命科学学院,鞍山师范学院化学与生命科学学院,鞍山师范学院化学与生命科学学院
基金项目:辽宁省自然基金项目(201602002),吉林省有机功能分子设计与合成重点实验室开放基金(130028652)和辽宁省教育厅项目(L2015003)资助。
摘    要:本文研究了合成官能化含5-羟基吡唑基的三芳基甲烷类化合物的a-二芳甲基-b-羰基硫代羧酸酯与肼的环合反应。研究表明,在乙醇介质中,回流条件下, a-二芳甲基-b-羰基硫代羧酸酯与肼能有效进行环合反应,高产率制得5-羟基吡唑基三芳甲烷类化合物。该反应条件温和,产率高,操作简单。

关 键 词:硫代羧酸酯  三芳基甲烷 环合反应 5-羟基吡唑
收稿时间:2017-05-30
修稿时间:2017-08-20

Cyclization of a-Diaryl methyl-b-oxothioesters and hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-ContainingTriarylmethanes
Ding Xuguang,Yu Haifeng,Zhao Hui and Yang Yong. Cyclization of a-Diaryl methyl-b-oxothioesters and hydrazine: Synthesis of Functionalized 5-Hydroxy Pyrazolyl-ContainingTriarylmethanes[J]. Chemistry, 2017, 80(12): 1152-1155
Authors:Ding Xuguang  Yu Haifeng  Zhao Hui  Yang Yong
Affiliation:School of Chemistry and Life Science,Anshan Normal University,School of Chemistry and Life Science,Anshan Normal University,School of Chemistry and Life Science,Anshan Normal University,School of Chemistry and Life Science,Anshan Normal University
Abstract:We developed the cyclization reactions of ?-diaryl methyl-?-ketothioesters and hydrazine for the synthesis of functionalized 5-hydroxy pyrazolyl-containing triarylmethanes. Our studies had shown that the cyclization reactions of ?-diaryl methyl-?-ketothioesters and hydrazine smoothly performed in refluxing EtOH, affording functionalized 5-hydroxy pyrazolyl-containing triarylmethanes in excellent yield. Mild reaction conditions,easy work-up procedure, and excellent yields are some notable advantages of our work.
Keywords:thioester, triarylmethane, cyclization  reaction, 5-hydroxy  pyrazole
点击此处可从《化学通报》浏览原始摘要信息
点击此处可从《化学通报》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号