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Synthesis of the Arctic sponge alkaloid viscosaline and the marine sponge alkaloid theonelladin C
Authors:Benjamin J Shorey  Jack E Baldwin
Institution:Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK
Abstract:The synthesis of Arctic sponge alkaloid viscosaline (1) is achieved by using the Zincke reaction as the penultimate step. A key synthetic intermediate theonelladin C (6), itself a marine sponge natural product, is synthesised efficiently using a four-step sequence.
Keywords:Sponge  Alkaloid  Pyridine  Zincke reaction
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