Synthesis of the Arctic sponge alkaloid viscosaline and the marine sponge alkaloid theonelladin C |
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Authors: | Benjamin J Shorey Jack E Baldwin |
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Institution: | Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK |
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Abstract: | The synthesis of Arctic sponge alkaloid viscosaline (1) is achieved by using the Zincke reaction as the penultimate step. A key synthetic intermediate theonelladin C (6), itself a marine sponge natural product, is synthesised efficiently using a four-step sequence. |
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Keywords: | Sponge Alkaloid Pyridine Zincke reaction |
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