Enantiospecific synthesis of 1,3-disubstituted allenes by palladium-catalyzed coupling of propargylic compounds with arylboronic acids |
| |
| Authors: | Masahiro Yoshida Tatsuro Okada Kozo Shishido |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Sho-machi, Tokushima 770-8505, Japan |
| |
| Abstract: | An enantiospecific coupling of propargylic esters and carbonates with arylboronic acids has been developed using a palladium catalyst. Optically active 1,3-disubstituted allenes were synthesized with high enantiomeric excesses by carrying out the reactions under basic aqueous conditions. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
