The structures of three new shishididemniols from a tunicate of the family Didemnidae |
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| Authors: | Hirotsugu Kobayashi Kohtaro Okada Takashi Iwashita Nobuhiro Fusetani |
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| Institution: | a Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
b Suntory Institute for Bioorganic Research, Wakayamadai, Shimamoto-cho, Mishima-gun, Osaka 618-8503, Japan |
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| Abstract: | Three new serinolipid derivatives, shishididemniols C (1), D (2), and E (3), were isolated as antibacterial constituents of a tunicate of the family Didemnidae. Their planar structures were elucidated by interpretation of NMR and MS data, whereas the absolute stereochemistry was determined by chemical conversions. Shishididemniols C (3), D (4), and E (5) exhibited antibacterial activity against the fish pathogenic bacterium Vibrio anguillarum. |
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| Keywords: | Antibacterial Serinolipid Tunicate Vibrio anguillarum |
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