Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp. |
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Authors: | Yohei Takahashi Jane Fromont |
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Affiliation: | a Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan b Western Australian Museum, Locked Bag 49, Welshpool DC, WA 6986, Australia |
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Abstract: | Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity. |
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Keywords: | Metachromins L-Q Sesquiterpenoid quinones Sponge Spongia sp |
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