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Metachromins L-Q, new sesquiterpenoid quinones with an amino acid residue from sponge Spongia sp.
Authors:Yohei Takahashi  Jane Fromont
Affiliation:a Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan
b Western Australian Museum, Locked Bag 49, Welshpool DC, WA 6986, Australia
Abstract:Six new sesquiterpenoid quinones with an amino acid residue, metachromins L-Q (1-6), have been isolated from an Okinawan marine sponge Spongia sp. The structures and stereochemistry of 1-6 were elucidated on the basis of the spectroscopic data and chemical correlations. Metachromins L (1) and M (2) showed modest cytotoxicity.
Keywords:Metachromins L-Q   Sesquiterpenoid quinones   Sponge   Spongia sp
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