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Terpenoid metabolites of the nudibranch Hexabranchus sanguineus from the South China Sea
Authors:Wen Zhang  Margherita Gavagnin  Yue-Wei Guo  Ernesto Mollo  Guido Cimino
Affiliation:a Istituto di Chimica Biomolecolare, CNR, Via Campi Flegrei 34, 80078—Pozzuoli, Naples, Italy
b State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhang Jiang, Shanghai, 201203, PR China
c California Academy of Sciences, 857 Howard Street, San Francisco, CA 94103, USA
Abstract:Chemical analysis of the secondary metabolite pattern of the nudibranch Hexabranchus sanguineus collected from the South China Sea revealed the presence of both sesquiterpenoids and diterpenoids, exhibiting very different structural features. Two new molecules, compounds 1 and 4, were isolated together with known compounds 2 and 3, and chemically characterized. This is the first report of terpenoids from H. sanguineus. The remarkable diversity of metabolites possessed by H. sanguineus supports some recent phylogenetic studies that place the mollusc near the steam of the dorid nudibranch tree.
Keywords:Nudibranch   Hexabranchus sanguineus   Sesquiterpenes   Diterpenes
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