1-Protected 5-amido 1,2,3-triazoles via ruthenium-catalyzed [3+2] cycloaddition of azides and ynamides |
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Authors: | Sophie Oppilliart,Li Zhang,Pierre Thué ry,Jean-Christophe Cintrat |
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Affiliation: | a CEA, iBiTecS, Service de Chimie Bioorganique et de Marquage, Gif sur Yvette F-91191, France b Department of Chemistry, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong c DSM/DRECAM/SCM, bâtiment 125 CEA/Saclay 91191 Gif sur Yvette cedex, France |
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Abstract: | Ynamides react with various azides in the ruthenium-catalyzed Huisgen [3+2] cycloaddition reaction. This ruthenium-catalyzed azide-ynamide cycloaddition reaction yields 1-protected 5-amido 1,2,3-triazoles. |
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