Notable chenodeoxycholic acid oligomers—synthesis, characterization, and 7α-OR steric hindrance evaluation |
| |
| Authors: | HR Ferhat Karabulut Suad A Rashdan |
| |
| Institution: | a Department of Chemistry, Trakya University, Edirne 22030, Turkey
b Department of Chemistry, University of Missouri, Kansas City, MO 64110-2499, USA |
| |
| Abstract: | The steric hindrance of the 7α-OR group in bile acid derivatives is very different from the 12α-OR group. The effect of this difference in steric hindrance on the synthesis of cyclocholates has been evaluated with support from AM1 and MM2 calculations. The 13C NMR parameters for cheneodeoxycholic acid-based cyclocholates have been determined. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
