An organo-catalytic approach to the enantioselective synthesis of (R)-selegiline |
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| Authors: | Siva Kumar Talluri |
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| Institution: | Chemical Engineering and Process Development Division, National Chemical Laboratory, Pashan Road, Pune 411 008, India |
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| Abstract: | An efficient enantioselective synthesis of (R)-selegiline has been achieved by two routes, via proline-catalyzed α-aminooxylation as well as α-amination of phenylpropanaldehyde as the key step. |
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| Keywords: | Asymmetric reactions Organocatalysis Proline α-Aminooxylation α-Amination |
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