Preparation and Degradation Behaviors of Poly(L-lactide-co-glycolide-co-ε-caprolactone)/1,4-butanediamine Modified Poly(lactic-co-glycolic acid) Blend Film |
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| Authors: | Ziwei Zhou Wenjuan Liu Tianlong Huang Yanmin Zhao Ping Chen |
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| Institution: | 1. School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, P. R. China;2. Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine Polymers, Hunan University of Science and Technology, Xiangtan, P. R. China;3. Department of Orthopedics, the Second Xiangya Hospital, Central South University, Changsha, P. R. China |
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| Abstract: | AbstractPolymer blending is an attractive method for producing new polymer materials with excellent properties. In this work the blended polymers were prepared from poly(L-lactide-co-glycolide-co-ε-caprolactone) and 1,4-butanediamine modified poly(lactic-co-glycolic acid) (PLLGC/BMPLGA). The hydrophilicity was studied by static water contact angle tests. The in-vitro degradation behaviors of the PLLGC/BMPLGA blended films were investigated during various degradation periods. The results showed that the introduction of the PLLGC reduced the hydrophilicity and degradation rate of the blended polymers while improved the tensile strength and elongation percentage. Therefore, we suggest the blends of the PLLGC and BMPLGA could supply a potential biomaterial for application in the medical field for use as tissue engineering scaffolds or drug delivery. |
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| Keywords: | Blending polymer poly(L-lactide-co-glycolide-co-ε-caprolactone) poly(lactic-co-glycolic acid) 14-butanediamine |
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