Schiff base supported mononuclear organotin(IV) complexes: Syntheses,structures and fluorescence cell imaging |
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| Authors: | Richa Vinayak Dhritiman Dey Dipanjan Ghosh Dhrubajyoti Chattopadhyay Abhrajyoti Ghosh Hari Pada Nayek |
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| Affiliation: | 1. Department of Applied Chemistry, Indian Institute of Technology (Indian School of Mines), Dhanbad‐826004, Jharkhand, India;2. Department of Biotechnology, University of Calcutta, Kolkata‐700019, West Bengal, India;3. NIPER Kolkata, Kolkata, India;4. Amity University, Kolkata, West Bengal, India;5. Department of Biochemistry, Bose Institute, Kolkata‐700054, West Bengal, India |
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| Abstract: | Three mononuclear organotin(IV) complexes supported by Schiff bases have been synthesized. The complexes [(C6H5)2Sn(L)] ( 1 ), [(t‐Bu)2Sn(L)] ( 2 ) and [(t‐Bu)2Sn(L')] ( 3 ) (L, L' = deprotonated Schiff bases) were obtained in good yield by the reaction of Schiff bases H 2 L or H 2 L′ with corresponding diorganotin dichlorides respectively. All newly synthesized complexes were characterized by means of FT‐IR spectroscopy, elemental analysis and multinuclear (1H, 13C and 119Sn) NMR spectroscopy. In addition, single crystal X‐ray diffraction analyses were employed to establish the solid state molecular structures of these complexes. The structures of 1 – 3 reveal that all complexes are mononuclear with a five‐coordinated tin(IV) centre in it. The absorption and emission properties of all complexes have been investigated. Moreover, cytotoxicity and fluorescence cell imaging studies of theses complexes have been performed. |
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| Keywords: | cytotoxicity fluorescence cell imaging multinuclear NMR organotin(IV) Schiff bases |
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