Rhodium‐catalyzed ortho‐C‐H olefination of aromatic aldehydes employing transient directing strategy |
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| Authors: | Xi Liu Zhonghao Wang Qun Chen Ming‐yang He Liang Wang |
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| Institution: | School of Petrochemical Engineering and Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Changzhou University, Changzhou, P. R. China |
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| Abstract: | A Rhodium(III)‐catalyzed ortho‐C‐H olefination of aromatic aldehydes in the presence of catalytic amount of TsNH2 has been developed. The in situ generated imine intermediate from aldehyde and TsNH2 worked as a transient directing group. Both electron‐rich and electron‐deficient aromatic aldehydes were tolerated, affording the corresponding products in moderate to good yields. Importantly, the present protocol provides a straightforward access to olefinated aromatic aldehydes with aldehydes as the simple starting materials. |
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| Keywords: | aryl aldehydes C‐H activation olefination transient directing groups |
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