Claycop/hydrazine: A new and highly efficient recyclable/reusable catalytic system for 1,4‐disubstituted‐1,2,3‐triazole synthesis under solvent‐free conditions |
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| Authors: | Hanan M F Elnagdy Kongkona Gogoi Abdul A Ali Diganta Sarma |
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| Institution: | 1. Department of Chemistry, Dibrugarh University, Dibrugarh, Assam, India;2. Analytical Chemistry Group, Chemical Science and Technology Division, CSIR‐North East Institute of Science and Technology, Jorhat, India |
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| Abstract: | Clay‐supported copper(II) nitrate (claycop) has been used as an efficient catalyst for azide–alkyne cycloaddition reactions leading to 1,4‐disubstituted 1,2,3‐triazoles. The highly efficient claycop/hydrazine hydrate catalytic system affords triazoles in a few minutes (1–20 min) at room temperature, under mild and solvent‐free conditions. High regioselectivity, excellent yields, ease of claycop synthesis and recyclability/reusability of the catalyst are considered as practical merits of the protocol. |
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| Keywords: | 1 2 3‐triazoles alkyne azide claycop/hydrazine hydrate heterogeneous |
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