| 吲哚衍生物的1H NMR谱研究 |
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| 引用本文： | 周勇,姚霞君,恽榴红.吲哚衍生物的1H NMR谱研究[J].波谱学杂志,2002,19(4):409-413. |
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| 作者姓名： | 周勇 姚霞君 恽榴红 |
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| 作者单位： | 军事医学院毒物药物研究所, 北京 100850 |
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| 基金项目： | 国家 973基金资助项目 (G1 9980 5 1 1 1 4) |
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| 摘 要： | 通过对1H-1H COSY谱的分析, 鉴定了两个同分异构体吲哚衍生物取代基团的位置，并对其氢谱进行了分析，对其谱峰进行了归属. 比较了一系列吲哚衍生物类似物的的氢谱，发现其氢谱呈现一定规律，并分析了其原因.
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| 关 键 词： | 吲哚 1H-1H COSY 取代位置 归属 |
| 文章编号： | 1000-4556(2002)04-0409-05 |
| 收稿时间： | 2002-04-01 |
| 修稿时间： | 2002年4月1日 |
CHARACTERIZATION OF INDOLE DERIVATIVES BY 1H-1H COSY SPECTROSCOPY |
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| ZHOU Yong,YAO Xia-jun,YUN Liu-hong.CHARACTERIZATION OF INDOLE DERIVATIVES BY 1H-1H COSY SPECTROSCOPY[J].Chinese Journal of Magnetic Resonance,2002,19(4):409-413. |
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| Authors: | ZHOU Yong YAO Xia-jun YUN Liu-hong |
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| Institution: | Academy of Military Medical Science, Institute of Pharmacology and Toxicology, Beijing 100850, China |
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| Abstract: | Indole derivatives are important pharmaceutical compounds often used for anti-anxiety treatments. In this study, the structures of a serials of indole based compounds were determined by \{\}1H, \{\}1H-1H COSY, MS-FAB, IR and element analysis. The \{\}1H chemical shifts of the compounds were assigned. The positions of the substitute groups were determined by \{\}1H-1H COSY. The \{\}1H chemical shifts of different indole derivatives were compared. |
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| Keywords: | indole ~1H-~1 H COSY substitution position NMR spectroscopy |
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