Synthesis of diarylmethanes via a Friedel-Crafts benzylation using arenes and benzyl alcohols in the presence of triphenylphosphine ditriflate |
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| Authors: | Mohammad Mehdi Khodaei Ehsan Nazari |
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| Affiliation: | Department of Organic Chemistry and Nanoscience & Nanotechnology Research Center (NNRC), Razi University, Kermanshah 67149, Iran |
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| Abstract: | Triphenylphosphine ditriflate (TPPD) was found to be an efficient promoter for the Friedel-Crafts benzylation of arenes with benzyl alcohols in CH2Cl2 at room temperature. The good yields, the 1:1 molar ratio of arene and benzyl alcohol, the benzylation of chlorobenzene as a nonactivated aromatic compound at room temperature, and no by-product formation are the main advantages of this procedure. |
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| Keywords: | Arenes Benzylation Electrophilic aromatic substitution Mitsunobu reaction Phosphorus |
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