Intramolecular reactions of hydroperoxides and oxetanes: stereoselective synthesis of 1,2-dioxolanes and 1,2-dioxanes |
| |
Authors: | Dai Peng Dussault Patrick H |
| |
Institution: | Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588-0304, USA. |
| |
Abstract: | reactions: see text] The 5-exo openings of oxetanes by hydroperoxides proceed rapidly and stereospecifically to furnish 1,2-dioxolanes. The corresponding 6-exo cyclizations are slower and proceed with moderate stereoselectivity. In the case of hydroperoxy acetals, 5-exo nucleophilic transfer of alkoxide competes effectively with 6-exo attack by the hydroperoxide. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|