Mass spectrometric characterization of substituted 2-thiazolin-4-one derivatives |
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Authors: | Giorgi Gianluca Salvini Laura Attanasi Orazio A Filippone Paolino Santeusanio Stefania |
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Institution: | Dipartimento di Chimica e Centro Interdipartimentale di Analisi e Determinazioni Strutturali, Università degli Studi di Siena, via Aldo Moro, 53100 Siena, Italy. gianluca.giorgi@unisi.it |
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Abstract: | Electron ionization mass spectrometry was used for the structural characterization of substituted 2-thiazolin-4-one derivatives in the gas phase. The compounds follow common fragmentation pathways, producing ions whose abundances are dependent on the chemical nature of the substituent at position 2. Collision-induced dissociation tandem mass spectrometric experiments, carried out on both molecular ions and fragment ions produced in the source, allowed the elucidation of gas-phase decompositions. The presence of tautomeric forms is suggested for some ionic species. Rapid identification of a primary or secondary amine moiety at position 2 of the thiazoline ring can be achieved by the detection of characteristic fragmentations occurring both in the ion source and under the collision-induced dissociation regime. |
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Keywords: | thiazolines heterocycles electron ionization tandem mass spectrometry |
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