Mechanistic distinctions between agrin and laminin-1 induced aggregation of acetylcholine receptors |
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| Authors: | Lara K Lee Dennis D Kunkel Jes Stollberg |
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| Institution: | 1. Békésy Laboratory of Neurobiology, University of Hawaii at Manoa, Honolulu, HI, 96822, USA
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| Abstract: | Background One of the earliest steps in synaptogenesis at the neuromuscular junction is the aggregation of nicotinic acetylcholine receptors
at the postsynaptic membrane. This study presents quantitative analyses of receptor and α-Dystroglycan aggregation in response
to agrin and laminin-1, alone or in combination. |
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