Theory of proton-transfer reactions. The influence of adiabaticity on free energy relations

The influence of adiabaticity on free energy relations of proton-transfer reactions is investigated within the framework of the quantum-statistical mechanical rate theory. It is found that there may be both for the Brønsted plot and for the free energy dependence of the kinetic isotope effect qualitative differences between the non-adiabatic and the adiabatic case in the exergonic region.