| 表面增强拉曼光谱在毒品检测中的应用进展 |
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| 引用本文： | 董荣录,李绍飞,林东岳,陈慧,杨良保. 表面增强拉曼光谱在毒品检测中的应用进展[J]. 中国科学:化学, 2021, 0(3): 294-309 |
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| 作者姓名： | 董荣录 李绍飞 林东岳 陈慧 杨良保 |
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| 作者单位： | 中国科学院合肥物质科学研究院健康与医学技术研究所;中国科学技术大学;安徽中科赛飞尔科技有限公司 |
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| 基金项目： | 安徽省重点研究与开发计划(编号:1804d08020308和201904d07020009);国家科技重大专项(编号:2018ZX09J18112)资助项目。 |
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| 摘 要： | 表面增强拉曼光谱(surfaced-enhanced Raman spectroscopy, SERS)作为一种借助贵金属纳米材料可以增强目标分子信号的拉曼光谱技术,由于其具有指纹识别、高灵敏、高准确度、快速无损、不受水分子干扰等特点,在法庭科学领域中的痕量毒品检测方面逐渐受到人们的关注.SERS不仅用于毒品纯品的检测...
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| 关 键 词： | 表面增强拉曼光谱 毒品 增强基底 痕量检测 数据分析 |
Progress of the applications of surface-enhanced Raman spectroscopy in illicit drug detection |
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| Ronglu Dong,Shaofei Li,Dongyue Lin,Hui Chen,Liangbao Yang. Progress of the applications of surface-enhanced Raman spectroscopy in illicit drug detection[J]. Scientia Sinica Chimica, 2021, 0(3): 294-309 |
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| Authors: | Ronglu Dong Shaofei Li Dongyue Lin Hui Chen Liangbao Yang |
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| Affiliation: | (Institute of Health&Medical Technology,Hefei Institutes of Physical Science,Chinese Academy Sciences,Hefei 230031,China;University of Science and Technology of China,Hefei 230026,China;Anhui CAS-SAFER Technology Co.,Ltd.,Hefei 230088,China) |
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| Abstract: | Surface-enhanced Raman spectroscopy(SERS)is a Raman spectroscopy technology that can enhance the analyte signal with the help of noble nanomaterials.Due to the merits of fingerprint recognition,high sensitivity,high accuracy,fast and non-destructive detection,and no interference from water.More and more attentions are being paid to SERS,especially in the application of trace drug-detection on site in forensic science.SERS is not only used for the detection of pure solutions,but also gradually expanded to complex,including seized drugs and human specimen.This review focused on the types and methods of SERS for the detection of drugs,introduced the development of enhanced substrates for drug detection,and the progress of SERS-based detection technology,and summarized the analysis methods of SERS data.Finally,we discussed the main challenges of SERS used on-site drug-detection and proposed the development trend of trace-detection based on SERS. |
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| Keywords: | surface-enhanced Raman spectroscopy illicit drug substrate trace detection data analysis |
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