Effect of nuclear magnetic resonance on chromosomes of mouse bone marrow cells |
| |
Authors: | N Prasad S C Bushong J I Thornby R N Bryan C F Hazlewood J E Harrell |
| |
Institution: | 1. Department of Radiology, Baylor College of Medicine, Houston, Texas, USA;2. Department of Psychiatry, Baylor College of Medicine, Houston, Texas, USA;3. Department of Physiology, Baylor College of Medicine, Houston, Texas, USA;4. Veterans Administration Medical Center at Houston USA |
| |
Abstract: | Three groups of six male Balb/c mice, subjected to 30 MHz continuous wave NMR exposure in a static magnetic field of 7.05 K Gauss for one hour, were each compared to another group of ten unexposed mice with respect to chromatid and chromosomal aberrations. The exposed groups were sacrificed at two hours, 24 hours and 48 hours following NMR exposure respectively. Control mice were sacrificed 24 hours after sham-exposure. All groups had approximately 0.02 apparent aberrations per cell. These apparent aberrations were in the form of metacentric chromosomes, possibly resulting from a union of chromosomes at their centromeres or possibly simply chromosomes in association. The results are consistent with earlier in vitro findings that NMR exposure causes no adverse cytogenetic effects. |
| |
Keywords: | Nuclear magnetic resonance Chromosome aberrations Bone marrow Mice |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|