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Cationic amphiphiles of both lipid and nonlipid nature in gene therapy
Authors:M A Maslov  E V Syicheva  N G Morozova  G A Serebrennikova
Institution:(1) M. V. Lomonosov State Academy of Fine Chemical Technology, 86 prosp. Vernadskogo, 117571 Moscow, Russian Federation
Abstract:The synthesis and biological activity of cationic lipids and cationic amphiphiles of different natures are considered. The general factors influencing the transfection efficiency are identified and summarized for various classes of compounds. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 385–400, March. 2000.
Keywords:cationic lipids  cationic liposomes  lipofection  gene therapy
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