Cationic amphiphiles of both lipid and nonlipid nature in gene therapy |
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Authors: | M A Maslov E V Syicheva N G Morozova G A Serebrennikova |
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Institution: | (1) M. V. Lomonosov State Academy of Fine Chemical Technology, 86 prosp. Vernadskogo, 117571 Moscow, Russian Federation |
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Abstract: | The synthesis and biological activity of cationic lipids and cationic amphiphiles of different natures are considered. The
general factors influencing the transfection efficiency are identified and summarized for various classes of compounds.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 385–400, March. 2000. |
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Keywords: | cationic lipids cationic liposomes lipofection gene therapy |
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