An efficient risk estimator with external information under additive hazards model |
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Authors: | Xin Wang Xiao-ming Xue Jie Zhou Liu-quan Sun |
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Institution: | 1.School of Science,Beijing Information Science and Technology University,Beijing,China;2.Academy of Mathematics and Systems Science,Chinese Academy of Sciences,Beijing,China;3.School of Mathematical Sciences,Capital Normal University,Beijing,China |
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Abstract: | Rare event data is encountered when the events of interest occur with low frequency, and the estimators based on the cohort data only may be inefficient. However, when external information is available for the estimation, the estimators utilizing external information can be more efficient. In this paper, we propose a method to incorporate external information into the estimation of the baseline hazard function and improve efficiency for estimating the absolute risk under the additive hazards model. The resulting estimators are shown to be uniformly consistent and converge weakly to Gaussian processes. Simulation studies demonstrate that the proposed method is much more efficient. An application to a bone marrow transplant data set is provided. |
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