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Synthetic studies on taxanes: A domino-enyne metathesis/Diels-Alder approach to the AB-ring |
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| Authors: | Krishna P. Kaliappan Velayutham Ravikumar Sandip A. Pujari |
| Affiliation: | (1) Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, 400 076, India |
| Abstract: | A domino enyne cross-metathesis/intramolecular Diels-Alder reaction has been successfully used to synthesize a bicyclo[5.3.1] undecene, corresponding to AB-ring of taxol without the gem dimethyl group. |
| Keywords: | Taxol RCM Grubbs catalyst IMDA Anticancer Domino reaction |
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