Thephysicochemical and biological properties of zinc(II) complexes |
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| Authors: | Erika Szunyogová Dagmar Mudroňová Katarína Györyová Radomíra Nemcová Jana Kovářová Lenka Piknová-Findoráková |
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| Affiliation: | (1) Department of Biophysics, Slovak Academy of Science, Košice, Slovak Republic, 040 01, Bulharská 6;(2) Research Institute of Gnotobiology and Prevention of Diseases in Young, University of Veterinary Medicine, Košice, Slovak Republic, 041 81, Komenského 73;(3) Department of Inorganic Chemistry, P. J. Šafarik University, Košice, Slovak Republic, 041 54, Moyzesova 11;(4) Institute of Macromolecular Chemistry AV ČR, Praha 6, Czech Republic, 162 06, Heyrovského nám. 2 |
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| Abstract: | Spectroscopic (IR), thermoanalytical (TG/DTG, DTA) and biological methods were applied to investigate physicochemical and biological properties of seven zinc(II) complex compounds of the following formula Zn(HCOO)2·2H2O (I), Zn(HCOO)2·tph (II), Zn(CH3COO)2·2H2O (III), Zn(CH3COO)2·tph (IV), Zn(CH3COO)2·2phen (V), Zn(CH3CH2COO)2·2H2O (VI), Zn(CH3CH2CH2COO)2·2H2O (VII), where tph=theophylline, phen=phenazone. The formation of various intermediates during thermal decomposition suggests the dependence on the length of aliphatic carboxylic chain and type of N-donor ligand (tph, phen). The final product of the thermal decomposition was ZnO. The antimicrobial activity of these complexes were tested against G+ and G– bacteria. Strong inhibitive effect was observed towards E. coli, salmonellae and Staph. aureus. |
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| Keywords: | antimicrobial activity complexes IR spectra thermal properties Zn(II) |
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