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A multi-component synthesis of 3-aryl-1-(arylmethylideneamino)pyrrolidine-2,5-diones |
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| Authors: | Mehdi Adib Samira Ansari Hamid Reza Bijanzadeh |
| Institution: | a School of Chemistry, University College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran b Department of Chemistry, Tarbiat Modarres University, PO Box 14115-175, Tehran, Iran c Chemistry Department, Zhejiang University, Hangzhou 310027, PR China |
| Abstract: | A multi-component synthesis of 3-aryl-1-(arylmethylideneamino)pyrrolidine-2,5-diones is described. A mixture of N-isocyaniminotriphenylphosphorane, an aldehyde, and Meldrum's acid undergo a 1:2:1 addition reaction under mild conditions to afford the title compounds in good to excellent yields. |
| Keywords: | N-Isocyaniminotriphenylphosphorane Aldehydes Meldrum's acid 3-Aryl-1-(arylmethylideneamino)pyrrolidine-2 5-diones Multi-component reactions |
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