|
|||||
|
|
Diastero- and enantioselective intramolecular carbometalation reaction |
|
| Authors: | Rozalia Unger Ilan Marek |
| Institution: | a Mallat Family Laboratory of Organic Chemistry, Schulich Faculty of Chemistry and the Lise Meitner-Minerva Center for Computational Quantum Chemistry, Technion-Israel Institute of Technology, 32000 Haifa, Israel b Department of Chemistry, University of Pittsburgh, PA 15260, USA |
| Abstract: | The zinc-catalyzed addition of various alkynes to acylsilanes followed by a Zn-Brook rearrangement and either the Zn-ene-allene or Zn-yne-allene cyclization led to the enantio- and diastereoselective formation of carbocycles in a single-pot operation. |
| Keywords: | Brook rearrangement Zn-ene-allene cyclization Enantioselective alkynylation Carbometalation Asymmetric catalysis |
| 本文献已被 ScienceDirect 等数据库收录！ | |