One-pot synthesis of highly substituted indolines |
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| Authors: | Kevin G Liu Jennifer R Lo Albert J Robichaud |
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| Institution: | Neuroscience Chemistry, Pfizer Global Research and Development, CN 8000, Princeton, NJ 08543, USA |
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| Abstract: | A general and convenient one-pot synthesis of highly substituted indolines from arylhydrazines and aldehydes is reported. This synthesis allows introduction of substitution at essentially all positions of the indoline nucleus to achieve significant diversity in this biologically important template. |
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