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An expeditious asymmetric formal synthesis of the antibiotic platensimycin |
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| Authors: | Konrad Tiefenbacher Johann Mulzer Andreas Pfaltz |
| Institution: | a University of Vienna, Institute of Organic Chemistry, Währingerstrasse 38, 1090 Wien, Austria b Department of Chemistry, University of Basel, St. Johanns-Ring 19, 4056 Basel, Switzerland |
| Abstract: | A short enantioselective and protecting group free access to the novel antibiotic platensimycin is reported. The crucial stereogenic information is provided by iridium catalyzed asymmetric hydrogenation. |
| Keywords: | Asymmetric synthesis Catalytic hydrogenation Natural products Antibiotics Polycyclic compounds |
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