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Simple and one-pot synthesis of tri and tetracyclic frameworks containing [1,8]naphthyridin-2-one moiety from the Baylis-Hillman adducts
Authors:Deevi Basavaiah  Kanumuri Ramesh Reddy
Institution:School of Chemistry, University of Hyderabad, Central University (PO), Gachibowli, Hyderabad 500 046, India
Abstract:A facile synthesis of tri and tetracyclic frameworks containing 1,8]naphthyridin-2-one skeleton from the Baylis-Hillman alcohols via the Johnson-Claisen rearrangement, followed by the treatment with Fe/AcOH in simple one-pot multi-step process is described.
Keywords:Baylis-Hillman reaction  Johnson-Claisen rearrangement  Reduction  Cyclization  [1  8]naphthyridin-2-ones  Fe/AcOH  DABCO
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