Metal-free intramolecular cyclopropanation of alkenes through iodonium ylide methodology |
| |
| Authors: | Robert M Moriarty Sachin Tyagi Mark Kinch |
| |
| Institution: | University of Illinois at Chicago, 845 W. Taylor St., Chicago, IL 60607, USA |
| |
| Abstract: | Intramolecular cyclopropanation of alkenes occurs thermally with iodonium ylides in the absence of conventional metal catalysts such as Rh(II) and Cu(II). In rigid molecular systems conversions are near quantitative. A mechanism is proposed involving formal 2+2 cycloaddition followed by reductive elimination of PhI to yield the cyclopropane. |
| |
| Keywords: | Metal-free Hypervalent iodine Cyclopropanation Cyclopropyl keto-esters Iodonium ylide |
| 本文献已被 ScienceDirect 等数据库收录！ |
