Efficient synthesis of 9H-pyrrolo[1,2-a]indol-9-one derivatives based on active manganese dioxide promoted intramolecular cyclization |
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Authors: | Francesca Aiello Fedora Grande |
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Affiliation: | Dipartimento di Scienze Farmaceutiche, Università della Calabria, Arcavacata di Rende 87036, Cosenza, Italy |
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Abstract: | A series of 9H-pyrrolo[1,2-a]indol-9-ones have been prepared via in-situ sequential oxidation of [2-(1H-pyrrol-1-yl)phenyl]methanols promoted by active manganese dioxide. The procedure led to title compounds in good yields under mild conditions, without the need to isolate the intermediate aldehydes. |
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Keywords: | 9H-Pyrrolo[1,2-a]indol-9-one 2-(1H-Pyrrol-1-yl)benzaldehyde Intramolecular cyclization Oxidation |
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