Catalytic enantioselective alkene epoxidation using novel spirocyclic N-carbethoxy-azabicyclo[3.2.1]octanones |
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| Authors: | Alan Armstrong Michela Bettati Andrew JP White |
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| Institution: | Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, UK |
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| Abstract: | A general synthetic route allowing access to several spirocyclic N-carbethoxy-azabicyclo3.2.1]octanones is developed. These novel ketones efficiently catalyse alkene epoxidation using Oxone® with up to 91.5% ee. |
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| Keywords: | Epoxidation Asymmetric Ketone Dioxirane |
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