SiO2@Fe2O3 core-shell nanoparticles for covalent immobilization and release of sparfloxacin drug |
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| Authors: | El-Gamel Nadia E A Wortmann Laura Arroub Karim Mathur Sanjay |
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| Affiliation: | Chemistry Department, Faculty of Science, Cairo University, 12613 Giza, Egypt. nadinealy@hotmail.com |
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| Abstract: | Silica-coated Fe(2)O(3) nanoparticles were synthesized as carriers for the covalent immobilization and release of antimicrobial drug sparfloxacin (SPFX). SPFX-loaded nanoparticles exhibited time-dependent drug release, with no measurable in vitro cytotoxicity, making the drug@nanoparticle conjugates potentially relevant for nanomedicine applications. |
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