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Synergistic N‐Heterocyclic Carbene/Palladium‐Catalyzed Reactions of Aldehyde Acyl Anions with either Diarylmethyl or Allylic Carbonates |
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| Authors: | Dr Shigeo Yasuda Takuya Ishii Shunsuke Takemoto Hiroki Haruki Prof Dr Hirohisa Ohmiya |
| Institution: | 1. http://seimitsu.w3.kanazawa‐u.ac.jp/eng/index;2. Division of Pharmaceutical Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan |
| Abstract: | Benzylation and allylation of aldehyde acyl anions were enabled by the merger of a thiazolium N‐heterocyclic carbene (NHC) catalyst and a palladium/bisphosphine catalyst in a synergistic manner. Owing to the mildness of the reaction conditions, various functional groups were tolerated in the substrates. |
| Keywords: | aldehydes ketones carbenes palladium synthetic methods |