Fuel‐Selective Transient Activation of Nanosystems for Signal Generation |
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| Authors: | Dr. Flavio della Sala Dr. Subhabrata Maiti Andrea Bonanni Prof. Dr. Paolo Scrimin Prof. Dr. Leonard J. Prins |
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| Affiliation: | 1. Department of Chemical Sciences, University of Padova, Padova, Italy;2. Current address: Department of Chemistry, The Pennsylvania State University, University Park, PA, USA |
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| Abstract: | The transient activation of function using chemical fuels is common in nature, but much less in synthetic systems. Progress towards the development of systems with a complexity similar to that of natural ones requires chemical fuel selectivity. Here, we show that a self‐assembled nanosystem, composed of monolayer‐protected gold nanoparticles and a fluorogenic peptide, is activated for transient signal generation only in case the chemical fuel matches the recognition site present at the nanoparticle surface. A modification of the recognition site in the nanosystem completely changes the chemical fuel selectivity. When two nanosystems are simultaneously present, the selectivity expressed by the system depends on the concentration of nucleotide added. |
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| Keywords: | dissipative self-assembly fluorescence gold nanoparticles supramolecular chemistry systems chemistry |
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