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A Comparison Between Full-COLD PCR/HRM and PCR Sequencing for Detection of Mutations in Exon 9 of PIK3CA in Breast Cancer Patients
Authors:Ghalamkari  Safoura  Khosravian  Farinaz  Mianesaz  Hamidreza  Kazemi  Mohammad  Behjati  Mohaddeseh  Hakimian  Sayyed Mohammadreza  Salehi  Mansoor
Institution:1.Department of Genetics and Molecular Biology, Isfahan University of Medical Sciences, Isfahan, Iran
;2.Medical Genetic Center of Genome, Isfahan, Iran
;3.Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
;4.Cancer Prevention Research Center, Isfahan University of Medical Science, Isfahan, Iran
;
Abstract:Applied Biochemistry and Biotechnology - One of the most common somatic mutations in breast cancer is found in PIK3CA with a prevalence rate of 18–45%. Different variants of this gene are...
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