高分子金属卟啉敏化剂的合成及其产生单线态氧的能力

本工作用氯甲基化的苯乙烯系的树脂和四-(对-氨基苯)卟啉及其Mg²⁺、Cd²⁺、Ni²⁺、Cu²⁺的络合物,合成了一组高分子的金属卟啉敏化剂。并用9,10-二甲基蒽作为¹O₂受体,测定了它们光敏化产生¹O₂的相对能力,分别为1.0、1.56、0.73、0.25、0.21。表明高分子卟啉镁具有较强的敏化能力,是一种良好的敏化剂,其他三种过渡金属元素,特别是具有顺磁性的Ni和Cu,对卟啉光敏化能力起了明显的抑制作用。

SYNTHESIS OF POLYMERIC METALLOPORPHYRINS SENSITIZERS AND THEIR ABILITY OF SINGLET OXYGEN PRODUCTION

A series of polymeric metalloporphyrins sensitizers were synthesized with chloro-methylated styrene resins, tetra-(pera-aminophenyl) porphyrin and their metal coplexes. The relative efficiency of photosensitized oxidation for 9, 10-dimethlanthrancene was determined with these sensitizers. The order of the sensitizing ability is: Mg²⁺ porphyrin > metal-free porphyrin>Cd²⁺ porphyrin>Ni²⁺ porphyrin>Cu²⁺ ponphyrin. The polymeric Mg²⁺ porphyrin is a good sensitizer for generating ¹O₂. The others, in particular the porphyrins containdnig paramagnetic Ni²⁺ and Cu²⁺, remarkably depress the formation of ¹O₂.