Transmission of extramembrane conformational change into current: construction of metal-gated ion channel |
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Authors: | Kiwada Tatsuto Sonomura Kazuhiro Sugiura Yukio Asami Koji Futaki Shiroh |
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Affiliation: | Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan. |
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Abstract: | Interaction with Fe(III) induces the reversible conformational switch of the extramembrane segment in the artificial receptor channel, which is transmitted into membranes as an increase in channel current (ion flux). |
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