7 Tesla MRA for the differentiation between intracranial aneurysms and infundibula |
| |
| Institution: | 1. Departments of Neurology, Leiden University Medical Center, Albinusdreef 2, PO Box 9600, 2300 RC Leiden, The Netherlands;2. Departments of Radiology, Leiden University Medical Center, Albinusdreef 2, PO Box 9600, 2300 RC Leiden, The Netherlands;3. Department of Radiation Sciences, Umeå, Sweden;4. C.J. Gorter Center for High Field MRI of the Leiden University Medical Center, Albinusdreef 2, PO Box 9600, 2300 RC Leiden, The Netherlands;1. Department of Radiology and Imaging Sciences, University of Utah, 729 Arapeen Drive, Salt Lake City, UT 84108, USA;2. Department of Bioengineering, University of Utah, 36 S Wasatch Drive, Rm 3100, Salt Lake City, UT 84112, USA;3. Siemens Medical Solutions, Inc., 660 First Avenue, 4th Floor, New York, NY 10016, USA;4. Siemens Medical Solutions, Inc., 729 Arapeen Drive, Salt Lake City, UT 84108, USA;5. Division of Nephrology, Department of Internal Medicine, University of Utah, 30 N 1900 E, Rm 4R312, Salt Lake City, UT 84132, USA;1. Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland;2. Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland;1. Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC, USA;2. Department of Medical Radiological Technologists, Technological Education Institute of Athens, Greece;3. Department of Radiology, University Hospital of Larissa, Larissa, Greece;4. Department of Medical Imaging, IASO Thessalias Hospital, Larissa, Greece;5. Department of Medical Instruments Technology, Techological Education Institute of Athens, Greece;6. Department of Radiology, General Hospital of Athens ‘G. Genimatas’, Athens, Greece;1. Medical Physics Laboratory, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy;2. Radiology and Diagnostic Imaging Department, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy;3. Department of Radiotherapy, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy;4. Department of Pathology, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy;5. Department of Otolaryngology & Head and Neck Surgery, Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy;1. Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany;2. Institute of Radiology, University Hospital Erlangen, Erlangen, Germany |
| |
| Abstract: | ObjectiveThe differentiation between an aneurysm and an infundibulum with time-of-flight MRA is often difficult. However, this distinction is important because it affects further patient follow-up. The purpose of this study was to assess the added value of high resolution 7 Tesla MRA for investigating small vascular lesions suspect for an aneurysm or an infundibulum.Materials and methodsWe included patients in whom an intracranial vascular lesion was detected in our University Hospital and in whom the discrimination between a true aneurysms or an infundibulum could not be made on conventional 1.5 or 3 T MRI were included in the study. All patients underwent an additional 7 T time-of-flight MRA at higher spatial resolution.ResultsWe included 6 patients. The age range of the patients was 35–65 years and 5 of them were women. 1 out of 6 had a 1.5 T MRI, the other 5 patients had a 3 T MRI previous to the 7 T MRI. The lesion size varied between 0.9 mm and 2.0 mm. In 5 of the 6 patients the presence of an infundibulum could be proven using the high resolution of the 7 T MRA. All patients tolerated the 7 T MRI well.ConclusionOur results suggest that high resolution and contrast of 7 T MRA provides added diagnostic value in discriminating between intracranial aneurysms and infundibula. This finding may have important consequences for patient follow-up and comfort because it might reduce unnecessary follow-up exams and decrease uncertainty about the diagnosis. Larger studies, however, are needed to confirm our findings. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
