Multispectral 3D phase-encoded turbo spin-echo for imaging near metal: Limitations and possibilities demonstrated by simulations and phantom experiments |
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| Institution: | 1. Image Sciences Institute, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands;2. Department of Orthopedics, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, The Netherlands;1. School of Electronic Engineering, Jilin University, Changchun, Jilin, China;2. Department of Radiology, Provincial Hospital of Fujian Province, Teaching Hospital of Fujian Medical University, Fuzhou, China;3. Department of Radiology, University of Pennsylvania, Philadelphia 19104, USA;4. School of Electronic Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan 611731, China;1. Mayo Graduate School, Biomedical Engineering and Physiology Track, Mayo Clinic, Rochester, Minnesota, USA;2. Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA;3. Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA;1. Department of Medicine, Section of Cardiology, The University of Chicago, Chicago, IL, United States;2. Department of Surgery, Section of Cardiothoracic Surgery, The University of Chicago, Chicago, IL, United States;3. Department of Radiology, The University of Chicago, Chicago, IL, United States;4. Philips, Gainesville, FL, United States.;1. Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA;2. Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, USA;3. Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA;4. UCSF/UC Berkeley Joint Graduate Group in Bioengineering, San Francisco, CA, USA;5. Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA;1. Department of Radiation Sciences, Umeå University, Umeå, Sweden;2. Department of Radiology, Uppsala University Hospital, Uppsala, Sweden;3. Applied Science Laboratory, GE Healthcare, Uppsala, Sweden |
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| Abstract: | To see improvements in the imaging performance near biomaterial implants we assessed a multispectral fully phase-encoded turbo spin-echo (ms3D-PE-TSE) sequence for artifact reduction capabilities and scan time efficiency in simulation and phantom experiments.For this purpose, ms3D-PE-TSE and ms3D-TSE sequences were implemented to obtain multispectral images (± 20 kHz) of a cobalt-chromium (CoCr) knee implant embedded in agarose. In addition, a knee implant computer model and the acquired ms3D-PE-TSE images were used to investigate the possibilities for scan time acceleration using field-of-view (FOV) reduction for off-resonance frequency bins and compressed sensing reconstructions of undersampled data. Both acceleration methods were combined to acquire a + 10 kHz frequency bin in a second experiment.The obtained ms3D-PE-TSE images showed no susceptibility related artifacts, while ms3D-TSE images suffered from hyper-intensity artifacts. The limitations of ms3D-TSE were apparent in the far off-resonance regions (±10–20] kHz) located close to the implant. The scan time calculations showed that ms3D-PE-TSE can be applied in a clinically relevant timeframe (~ 12 min), when omitting the three central frequency bins. The feasibility of CS acceleration for ms3D-PE-TSE was demonstrated using retrospective reconstructions before combining CS and rFOV imaging to decrease the scan time for the + 10 kHz frequency bin from ~ 10.9 min to ~ 3.5 min, while also increasing the spatial resolution fourfold. The temporally resolved signal of ms3D-PE-TSE proved to be useful to decrease the intensity ripples after sum-of-squares reconstructions and increase the signal-to-noise ratio.The presented results suggest that the scan time limitations of ms3D-PE-TSE can be sufficiently addressed when focusing on signal acquisitions in the direct vicinity of metal implants. Because these regions cannot be measured with existing multispectral methods, the presented ms3D-PE-TSE method may enable the detection of inflammation or (pseudo-)tumors in locations close to the implant. |
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