Solid phase synthesis of a prototype of a new class of biomimetic receptors for anionic carbohydrates |
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| Authors: | Schmuck Carsten Heller Maija |
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| Affiliation: | Universit?t Würzburg, Institut für Organische Chemie, Am Hubland, 97074 Würzburg, Germany. schmuck@chemie.uni-wuerzburg.de |
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| Abstract: | A solid phase synthesis for a new biomimetic receptor was developed. First binding studies show that binds anionic carbohydrates such as glucose-1-phosphate and cAMP with association constants in the lower millimolar range in 20% buffered water in DMSO using both polar and apolar interactions. |
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