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| Efficient DNA Cleavage by Copper(Ⅱ) Complex Derived from 1, 1′-Dimethyl-2, 2′-biimidazole Ligand | |
| 作者姓名： | Rui Li SANG Pin YANG Institute of Molecular Science Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education Shanxi University Taiyuan 030006 |
| 作者单位： | Rui Li SANG，Pin YANG Institute of Molecular Science，Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education，Shanxi University，Taiyuan 030006 |
| 摘 要： | Artificial enzymes are non-protein molecules that are simpler than natural enzymes,but they also possess high efficiency and specificity.Artificial metallonucleases have been proven to be an efficient tools for the footprinting and sequencespecific targeting of nucleic acid1,2.In recent years,the study of enzyme model is one of the most active fields,especially chemical nuclease3.The binding of copper ions to DNA is well established as they have ability to cleave DNA,particularly when Cu(I… |
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