Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the 'click' labelling of biomolecules |
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| Authors: | Patra Malay Metzler-Nolte Nils |
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| Institution: | Lehrstuhl für Anorganische Chemie I, Bioanorganische Chemie, Fakult?t für Chemie und Biochemie, Ruhr-Universit?t Bochum, Universit?tsstr. 150, 44801, Bochum, Germany. |
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| Abstract: | A convenient synthesis of azidomethyl-ruthenocene and its use in the covalent labelling of amino acids, peptides and a peptide nucleic acid (PNA) monomer derivative by Cu(I) catalyzed azide-alkyne coupling (Cu-AAC, "click chemistry") are described. |
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