|
|||||
|
|
Synthesis of regiospecifically polysubstituted pyridazinones |
|
| Authors: | João X de Araújo-Júnior Martine Schmitt Cyril Antheaume Jean-Jacques Bourguignon |
| Institution: | a Institut Gilbert Laustriat, UMR 7175, 74 route du Rhin, BP 60024, 67401 Illkirch, France b Service Commun de RMN, Faculté de Pharmacie, 74 route du Rhin, BP 60024, 67401 Illkirch, France c Escola de Enfermagem e Farmacia, Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, cidade Universitaria, 57.072-970 Maceió-AL, Brazil |
| Abstract: | Desymmetrization of pyridazine-3,6-diones by the use of N-benzyl protective groups leads to useful starting materials for building polysubstituted pyridazine libraries in a regioselective manner. |
| Keywords: | N-Benzyl 4 (5)-substituted pyridazine 3 6-diones amination Palladium cross coupling reaction Microwave heating Suzuki Sonogashira |
| 本文献已被 ScienceDirect 等数据库收录！ | |