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Non-extensive trends in the size distribution of coding and non-coding DNA sequences in the human genome
Authors:Th Oikonomou  A Provata
Institution:(1) Institute of Physical Chemistry, National Center for Scientific Research “Demokritos”, 15310 Athens, Greece;(2) Department of Biological Chemistry, University of Athens, School of Medicine, Goudi, 11527 Athens, Greece
Abstract:We study the primary DNA structure of four of the most completely sequenced human chromosomes (including chromosome 19 which is the most dense in coding), using non-extensive statistics. We show that the exponents governing the spatial decay of the coding size distributions vary between 5.2 ≤r ≤5.7 for the short scales and 1.45 ≤q ≤1.50 for the large scales. On the contrary, the exponents governing the spatial decay of the non-coding size distributions in these four chromosomes, take the values 2.4 ≤r ≤3.2 for the short scales and 1.50 ≤q ≤1.72 for the large scales. These results, in particular the values of the tail exponent q, indicate the existence of correlations in the coding and non-coding size distributions with tendency for higher correlations in the non-coding DNA.
Keywords:89  75  Fb Structures and organization in complex systems  89  75  Da Systems obeying scaling laws  87  14  Gg DNA  RNA
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