Multiscale multimodal imaging with multiphoton microscopy and optical coherence tomography |
| |
Authors: | Tang Shuo Zhou Yifeng Chan Kenny K H Lai Tom |
| |
Institution: | Department of Electrical and Computer Engineering, University of British Columbia, Vancouver, BC, Canada. tang@ece.ubc.ca |
| |
Abstract: | A multiscale multiphoton microscopy (MPM) and optical coherence tomography (OCT) system has been developed using a sub-10 fs Ti:sapphire laser. The system performs cross-sectional OCT imaging over millimeter field-of-view and en-face high-resolution MPM imaging with submicrometer resolution from the same sample location. With fish cornea, we have demonstrated cross-sectional imaging of cornea tissue layers using OCT, and the zoom-in imaging of cells and collagen fibers in each layer using MPM. The multiscale MPM/OCT system shows the potential of a rapid coarse scan to search for abnormal regions and the subsequent fine zoom-in imaging for diagnosis. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|