The Robert Robinson Laboratories, University of Liverpool, P.O. Box 147, Liverpool, England
Abstract:
The synthesis of the 1–16 fragment of a lysozyme analogue is described. Three protected subfragments 1-4, 5-10 and 11-16 were combined using the N, N'-dicyclohexylcarbodiimide/N-hydroxysuccinimide method. The fully protected hexadecapeptide was purified by gel filtration on Sephadex LH-60 eluting with N-methylpyrrolidone.